dietary iron deprivation / colitis
Question:
- Hide quoted text — Show quoted text – >You also have to remember that nutrients work in synergy.Also that there is >a bit more to anemia than just iron.If one is low in iron one is low in >other nutrients also. > >It appears that the development of vitamin E deficiency anemia occurs in > >infants receiving iron supplementation. > I’ve heard DO NOT give iron to infants. To much of any good thing is > bad for you. that includes antioxidants.
good point. good health is definately a balancing act of sorts. The take a vitamin pill and you will be healthy philosophy kinda falls apart. good food, excersise, cleanliness, these fight disease. nice chat Ken. Tired of the flames
Response:
>It appears that the development of vitamin E deficiency anemia occurs in >infants receiving iron supplementation.
I’ve heard DO NOT give iron to infants. To much of any good thing is bad for you. that includes antioxidants.
Response:
You also have to remember that nutrients work in synergy.Also that there is a bit more to anemia than just iron.If one is low in iron one is low in other nutrients also.
– Hide quoted text — Show quoted text ->It appears that the development of vitamin E deficiency anemia occurs in >infants receiving iron supplementation. > I’ve heard DO NOT give iron to infants. To much of any good thing is > bad for you. that includes antioxidants.
Response:
>So is this study saying you should have *less* iron to help your IBD? Sounds >good but what about the whole anemia and possible dying thing ? >If this study were applicable to humans then many people with chrons/colitis >would automatically be cured because a lot of them have seriously low serum >iron. (What due to the bleeding & all.) >Red meat of course is the best source of serum iron. I’ve known a few vegans >in my day who’ve gone through menopause, almost died of anemia because they >were iron deficient in the first place, and then switched to eating red meat >because I guess they figured it was either them or "Bossy".
I have to agree. dont really know what he’s driving at, but I do know lack of iron is a bad thing.
Response:
>So is this study saying you should have *less* iron to help your IBD? Sounds >good but what about the whole anemia and possible dying thing ?
Dying .. from anemia .. ? Which anemia are they dying from ..? The same anemia CREATED by FEEDING .. iron ..? <<snip>> It appears that the development of vitamin E deficiency anemia occurs in infants receiving iron supplementation. Publication Types: Clinical Trial Randomized Controlled Trial PMID: 1117912 [PubMed - indexed for MEDLINE] <<snip>> >If this study were applicable to humans then many people with chrons/colitis >would automatically be cured because a lot of them have seriously low serum >iron. (What due to the bleeding & all.)
DIETARY IRON DEPRIVATION .. No iron IN the .. gut .. >Red meat of course is the best source of serum iron. I’ve known a few vegans >in my day who’ve gone through menopause, almost died of anemia because they >were iron deficient in the first place, and then switched to eating red meat >because I guess they figured it was either them or "Bossy".
How come I don’t believe you .. Who loves ya. Tom Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking
Response:
So is this study saying you should have *less* iron to help your IBD? Sounds good but what about the whole anemia and possible dying thing ? If this study were applicable to humans then many people with chrons/colitis would automatically be cured because a lot of them have seriously low serum iron. (What due to the bleeding & all.) Red meat of course is the best source of serum iron. I’ve known a few vegans in my day who’ve gone through menopause, almost died of anemia because they were iron deficient in the first place, and then switched to eating red meat because I guess they figured it was either them or "Bossy".
Response:
Int J Colorectal Dis. 2004 Apr 6 [Epub ahead of print] Related Articles, Links Effects of iron deprivation or chelation on DNA damage in experimental colitis. Barollo M, D’Inca R, Scarpa M, Medici V, Cardin R, Fries W, Angriman I, Sturniolo GC. Department of Surgical and Gastroenterological Sciences, University of Padua, Via Giustiniani 2, Italy, 35128, Padova. BACKGROUND AND AIMS. In inflammatory bowel diseases iron contributes to the formation of DNA adducts through the production of hydroxyl radicals. The aim of our study was to evaluate the effects of dietary or pharmacological iron deprivation in an experimental model of colitis in the rat and its potential protective effect against DNA damage. METHODS. Colitis was induced in rats by intracolonic instillation of dinitrobenzene sulphonic acid. Rats were assigned to an iron-deprived diet or to desferrioxamine preceding the induction of colitis. The severity of colitis was assessed by the presence of bloody diarrhea, colonic macroscopic damage score, body-weight variations and the amount of DNA colonic adducts. Hepatic and colonic iron concentrations were measured. RESULTS. Treated rats experienced less diarrhea and did not lose weight in comparison to untreated animals. The macroscopic damage score was significantly reduced in the iron-deprived diet for the 5-week group ( P=0.03). Liver and colonic iron levels were significantly more reduced in the iron-deprived groups than in the standard diet group ( P<0.03 and P<0.01 after a 3- and 5-week iron-deprived diet, respectively). DNA adduct formation was significantly reduced in the groups deprived of iron for 5 weeks ( P<0.001) or treated with desferrioxamine ( P<0.01). CONCLUSIONS. The degree of colitis caused by DNBS is macroscopically improved by dietary iron deprivation and to a lesser extent by pharmacological chelation; genomic damage is reduced by dietary iron deprivation or chelation, and this may have clinical implications on cancer prevention. PMID: 15067556 [PubMed - as supplied by publisher] —— Who loves ya. Tom Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking
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